If you plan on gaming on Debian, you're going to want Lutris. It's taken the cumbersome process of installing and playing games with Wine and automated everything to a point that makes everything nearly as easy as on Windows. Lutris is available from the developers through a Debian repository, so all you need to do is add it to your system to get started.
This is a companion discussion topic for the original entry at https://linuxconfig.org/how-to-install-lutris-on-debian-10-buster